Neonatal Procalcitonin Intervention Study (NeoPInS): Effect of Procalcitonin-guided decision making on Duration of antibiotic Therapy in suspected neonatal early-onset Sepsis: A multi-centre randomized superiority and non-inferiority Intervention Study

Table 1 Risk of infection classification categories

Category 4: Low risk (Infection unlikely)	One abnormal finding:
	- pre/perinatal risk factor*, OR
	- suspect clinical symptom*, OR
	- abnormal laboratory examination*
Category 3: Intermediate risk (Infection possible)	Two abnormal findings:
	- pre/perinatal risk factors*, AND/OR
	- suspect clinical symptoms*, AND/OR
	- abnormal laboratory examinations*
Category 2: High risk (Infection probable)	Three abnormal findings:
	- pre/perinatal risk factors*, AND/OR
	- suspect clinical symptoms*, AND/OR
	- abnormal conventional laboratory examinations*
Category 1: Proven infection	≥ 1 abnormal finding (pre/perinatal risk factors, clinical symptoms, laboratory examinations) AND a positive culture

The assessment of risk of infection classification is independent of serum PCT levels.
* See assessment guidelines (Table 2)

ISSN: 1471-2431