Table 1 Characteristics of the ELBW infants in this study
Group 1 | Group 2 | Group 3 | p-value* | |
|---|---|---|---|---|
(1997–2000) | (2001–2005) | (2006–2009) | ||
(N = 65) | (N = 178) | (N = 172) | ||
Gestational age (w) | 27.0 (26–28) | 27.0 (25.6-29.0) | 26.9 (25.7-28.8) | 0.988 |
Birth weight (g) | 814 (680–935) | 800 (700–915) | 800 (700–900) | 0.903 |
IUGR | 24 (38.1%) | 63 (36.0%) | 62 (39.0%) | 0.773 |
Multiple gestation | 21 (32.3%) | 60 (33.7%) | 69 (40.1%) | 0.180 |
Male gender | 26 (40%) | 92 (51.7%) | 80 (46.5%) | 0.684 |
Chorioamnionitis | 5 (7.7%) | 31 (17.4%) | 45 (26.2%) | 0.004 |
Antibiotics (mother) | 40 (62.5%) | 104 (62.3%) | 101 (62.7%) | 0.956 |
Prenatal steroids | 52 (81.3%) | 165 (96.5%) | 157 (91.8%) | 0.097 |
Cesarean section | 44 (67.7%) | 121 (68.8%) | 101 (59.1%) | 0.098 |
Apgar at 1 min ≤3 | 19 (30.2%) | 26 (14.6%) | 21 (12.3%) | 0.004 |
Apgar at 5 min ≤6 | 11 (16.9%) | 25 (14.3%) | 25 (15.2%) | 0.836 |
Umbilical artery pH | 7.23 (7.13-7.30) | 7.27 (7.21-7.32) | 7.27 (7.17-7.32) | 0.019 |
- Not 9performed | 9 (13.8%) | 39 (21.9%) | 25 (14.5%) | 0.133 |
- Mask/IPPV + PEEP | 6 (9.2%) | 65 (36.5%) | 70 (40.7%) | <0.001 |
- ETI | 44 (67.7%) | 67 (37.6%) | 70 (40.7%) | <0.001 |
- ETI + ChC + E | 6 (9.2%) | 7 (3.9%) | 7 (4.1%) | 0.195 |
- ET intubation | 56 (86.2%) | 121 (68.0%) | 123 (71.5%) | 0.143 |
- Duration (days) | 4 (1–9) | 2 (0–5) | 2 (0–7) | 0.005 |