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Table 2 Morbidity and mortality in ELBW infants

From: Trends in survival among extremely-low-birth-weight infants (less than 1000 g) without significant bronchopulmonary dysplasia

 

Group 1

Group 2

Group 3

p-value*

(1997–2000)

(2001–2005)

(2006–2009)

 

(N = 65)

(N = 178)

(N = 172)

 

CRIB

3 (1–8)

4 (2–7)

4 (2–8)

0.722

RDS

36 (55.4%)

99 (55.6%)

103 (59.9%)

0.432

Sepsis

28 (43.1%)

85 (47.8%)

65 (37.8%)

0.215

NEC

6 (9.2%)

12 (6.7%)

12 (7.0%)

0.644

IVH

18 (27.7%)

36 (20.2%)

43 (25.0%)

0.999

- Grades III/IV

11 (16.9%)

16 (9.0%)

18 (10.5%)

0.307

PVLM

1 (4.5%)

5 (5.6%)

4 (2.3%)

0.245

PDA

17 (26.2%)

56 (31.5%)

75 (43.6%)

0.004

- Surgical closure

1 (1.5%)

12 (6.7%)

18 (10.5%)

0.058

Parenteral nutrition (day)

13 (7–20)

9 (6–13)

8 (6–12)

0.009

Formula feed

24 (45.3%)

40 (25.2%)

17 (11.1%)

<0.001

Mortality**

23 (35.4%)

43 (24.2%)

40 (23.3%)

0.102

SWsBPD

38 (58.5%)

132 (74.2%)

129 (75.0%)

0.032

In survivors:

n = 42

n = 135

n = 132

 

Mild BPD

8 (19.0%)

34 (25.2%)

39 (29.5%)

0.378

Moderate or severe BPD

4 (9.5%)

3 (2.2%)

3 (2.3%)

0.046

Weight at discharge (g)

2148 (2100–2250)

2060 (1900–2160)

2013 (1900–2193)

<0.001

Length of stay (days)

83 (64–102)

70 (59–83)

71 (59–85)

0.007

Weight gain (g/kg/day)

16 (14–18)

17 (15–19)

17 (15–19)

0.233

  1. CRIB: clinical risk index for babies; RDS: respiratory distress syndrome; NEC: necrotizing enterocolitis; IVH: peri-intraventricular hemorrhage; PVLM: periventricular leukomalacia; PDA: patent ductus arteriosus; SWsBPD: survival without significant bronchopulmonary dysplasia.
  2. Median (IQR: 25th-75th percentile), number (%).
  3. * Kruskal-Wallis or chi-square test; ** All deaths occurred in the NICU.