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Table 3 Differences between survivors without significant BPD and deceased or surviving infants with significant BPD

From: Trends in survival among extremely-low-birth-weight infants (less than 1000 g) without significant bronchopulmonary dysplasia

 

SWsBPD

Deceased/Significant BPD

p-value*

(n = 299)

(n = 116)

Year of birth

  

0.032

- 1997–2000

38 (58.5%)

27 (41.5%)

 

- 2001–2005

132 (74.2%)

46 (25.8%)

 

- 2006–2009

129 (75.0%)

43 (25.0%)

 

Gestational age (w)

27.6 (26.1-29.4)

25.4 (24.4-27.0)

<0.001

Birth weight (g)

850 (750–935)

680 (589–780)

<0.001

IUGR

112 (38.5%)

37 (34.9%)

0.515

Multiple gestation

102 (34.1%)

48 (41.4%)

0.167

Male gender

135 (45.2%)

63 (54.3%)

0.094

Chorioamnionitis

48 (16.1%)

33 (28.4%)

0.004

Antibiotics (mother)

167 (59.6%)

78 (69.6%)

0.065

Prenatal steroids

277 (95.2%)

97 (84.3%)

<0.001

Cesarean section

213 (72.0%)

53 (45.7%)

<0.001

Apgar at 1 minute ≤3

29 (9.7%)

37 (32.5%)

<0.001

Apgar at 5 minutes ≤6

29 (9.7%)

32 (28.3%)

<0.001

Umbilical artery pH

7.26 (7.17-7.31)

7.29 (7.19-7.32)

0.165

Resuscitation

  

<0.001

- Not performed

67 (22.4%)

6 (5.2%)

 

- Mask/IPPV + PEEP

121 (40.5%)

20 (17.2%)

 

- ET intubation

102 (34.1%)

79 (68.1%)

 

- ET Intubation +

   

chest compression +

   

epinephrine

9 (3.0%)

11 (9.5%)

 

CRIB

4 (1–6)

9 (7–13)

<0.001

RDS

146 (48.8%)

92 (79.3%)

<0.001

Mechanical ventilation

184 (61.5%)

116 (100%)

<0.001

Sepsis

124 (41.5%)

54 (46.6%)

0.349

NEC

17 (5.7%)

13 (11.2%)

0.052

IVH

52 (17.4%)

45 (38.8%)

<0.001

- Grades III/IV

11 (3.7%)

34 (29.3%)

<0.001

PVLM

6 (3.1%)

4 (4.5%)

0.536

PDA

105 (35.1%)

43 (37.1%)

0.710

- Surgical closure

25 (8.4%)

6 (5.2%)

0.268

Severe arterial

   

hypotension

10 (3.4%)

30 (26.1%)

<0.001

  1. CRIB: clinical risk index for babies; IUGR: intrauterine growth restriction; ET: endotracheal; RDS: respiratory distress syndrome; NEC: necrotizing enterocolitis; IVH: peri-intraventricular hemorrhage; PEEP: positive end expiratory pressure; PVLM: periventricular leukomalacia; PDA: patent ductus arteriosus; SWsBPD: survival without significant BPD.
  2. Median (IQR: 25th-75th percentile), number (%).
  3. * Mann–Whitney U or chi-square test.