Table 1 Data collected during follow-up phases of the Newcastle preterm birth growth study
Phase 1- Growth and Protein study RCTs | Phase 2- Cognitive/Behavioural follow-up at 10Â years | Phase 3- Early adolescent follow-up | Phase 4- Late adolescent follow-up |
|---|---|---|---|
(n = 247) | (n = 92 from 113 in growth study) | (n = 153 from 247 in RCTs) | (n = 60 from 153 in phase 3) |
Auxology: | Â | Auxology: | Auxology: |
Length*, weight, OFC at birth, discharge, term, 1,2,3,6,12,18,24 months corrected age | Wechsler Intelligence Scale for Children version 3 (WISC III) including Wechsler Objective Numerical Dimensions (WOND), Wechsler Objective Reading Dimensions (WORD) and Wechsler Objective Language Dimensions (WOLD). Achenbach Child Behaviour Checklist. Vineland adaptive behavior scales (n = 113) | Height, weight, OFC, abdominal circumference, waist/hip ratio | Height, weight, waist circumference, blood pressure. Self assessment of pubertal status |
Blood pressure | |||
Self-assessment of pubertal status | |||
|  |  | (n = 153) |  |
Bloods: | Â | Bloods: | Bloods: |
Serum Biochemistry weekly till term then 1,2,3Â months | Â | Short oral glucose tolerance test | 2Â hour glucose tolerance test, 25-OHD, lipid profile, liver function, sex hormones, RNA, cellular DNA and serum to store |
Fasting Lipids: cholesterol, triglycerides | |||
Leptin, adiponectin, insulin and IGF1 (n = 70 subset) |  | Leptin, adiponectin | |
|  |  | (n = 109) |  |
Body composition: | Â | Body composition: | Body composition: |
DXA at discharge and/or term, 3,6,12Â months (6 and 12Â months only growth study) | Â | DXA scan and bio-impedance | BODPOD |
(n = 139) | IHL and IMCL deposition using 1H magnetic resonance spectroscopy | ||
Social questionnaire | Socioeconomic deprivation score | Social and family history | SCRAN-24 dietary information |
Actigraph data | |||
Intervention and feedback questionnaires | |||
BSID II MDI and PDI at 18 m (Growth study n = 113) |  |  |  |