Differences in tidal breathing between infants with chronic lung diseases and healthy controls

BMC Pediatrics

Table 3 Comparison of TB parameters between both patient groups ordered according to the p-value of the ANOVA (Presented are group means ± SD, statistically significant p-values after Bonferroni correction (p < 0.0028) are printed in bold)

Parameter	Healthy neonates (n = 48)	CLD infants (n = 48)	p-value CLD
t_I(s)	0.65 ± 0.14	0.45 ± 0.11	p < 0.0001
RR (min^-1)	39.2 ± 8.6	55.4 ± 14.2	p < 0.0001
(PTIF+PTEF)/V_T (s^-1)	0.27 ± 0.06	0.37 ± 0.09	p < 0.0001
t_E (s)	0.98 ± 0.24	0.72 ± 0.22	p < 0.0001
V_T/t_I(mL·s^-1·kg^-1)	8.9 ± 2.2	11.6 ± 2.8	p < 0.0001
V'_E(mL·min^-1·kg^-1)	215 ± 51.7	276 ± 76.8	p < 0.0001
TIF 50 (L·min^-1·kg^-1)	0.75 ± 0.21	0.98 ± 0.26	p < 0.0001
PTIF (L·min^-1·kg^-1)	0.83 ± 0.20	1.05 ± 0.28	p < 0.0001
PTEF/t_PTEF (L·s^-2·kg^-1)	2.90 ± 1.68	5.25 ± 3.66	p = 0.0001
PTEF (L·min^-1·kg^-1)	0.64 ± 0.19	0.82 ± 0.29	p = 0.0006
t_ptef (s)^*)	0.24 ± 0.09	0.18 ± 0.11	p = 0.001
TEF75 (L·min^-1·kg^-1)	0.60 ± 0.20	0.76 ± 0.29	p = 0.003
TEF50 (L·min^-1·kg^-1)	0.52 ± 0.17	0.66 ± 0.25	p = 0.003
TEF25 (L·min^-1·kg^-1)	0.38 ± 0.11	0.46 ± 0.16	p = 0.006
V_ptef (mL/kg)^*)	1.68 ± 0.52	1.37 ± 0.44	p = 0.006
V_T (mL·kg^-1)	5.57 ± 1.06	5.15 ± 1.35	p = 0.09
V_PTEF/V_T(%)^*)	29.4 ± 6.6%	27.2 ± 6.1%	p = 0.13
t_PTEF/t_E (%)^*)	25.8 ± 9.7%	23.2 ± 7.8%	p = 0.20

^*)Loops with flow limitations, grunting or other deformations were excluded from the evaluation (6 controls, 8 CLD infants)
Abbreviations: t_I,E-inspiratory, expiratory time, RR-respiratory rate, PTIF, PTEF-peak tidal inspiratory and expiratory flow, V_T-tidal volume, TIF 50-tidal inspiratory flow when 50% of V_T is inspired, TEF 75, TEF 50, TEF 25-expiratory flow when 75%, 50% and 25% of tidal volume remains in the lung, V'_E-minute ventilation, t_PTEF,V_PTEF-time and volume to peak tidal expiratory flow

ISSN: 1471-2431