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Table 2 Cord/Plasma/Serum concentrations of glucose and cytokines with adjustments for parity, smoking, gestational age at birth and fetal sex

From: Mild gestational diabetes in pregnancy and the adipoinsular axis in babies born to mothers in the ACHOIS randomised controlled trial

 

GDM

Not GDM

 

Treatment Group

Routine Care Group

Control Group

 

Unadjusted

Adjusted*

Unadjusted

Adjusted*

Unadjusted

Adjusted*

Plasma Glucose (mmol/ml)

4.8

0.2

4.7

0.2+

5.0

0.2+

4.8

0.2+

4.5

0.1

4.3

0.2

Serum Insulin (μU/ml)^

2.0

0.1

2.0

0.2

2.2

0.1

2.2

0.2

2.1

0.1

2.0

0.1

Insulin to Glucose Ratio^

0.5

0.1

0.5

0.2

0.6

0.1

0.6

0.2

0.6

0.1

0.5

0.1

Serum Adiponectin (ng/ml)

23.0

1.7+

21.8

2.1+

24.3

1.5

23.2

2.0+

27.5

1.0

26.8

1.7

Serum Leptin (ng/ml)^

2.2

0.1

2.2

0.2

2.7

0.1#

2.6

0.1#

2.4

0.1

2.4

0.1

Adiponectin to Leptin Ratio^

0.8

0.2

0.8

0.2

0.5

0.1+

0.5

0.2+

0.8

0.1

0.8

0.1

  1. Figures are mean, standard error
  2. ^ Statistical analysis was performed on log-transformed data
  3. * Results adjusted for parity, smoking, gestational age at birth and fetal sex
  4. # p ≤ 0.05 versus GDM (Treatment Group)
  5. + p ≤ 0.05 versus Control Group