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Table 3 Cord Plasma/Serum concentrations of glucose and cytokines with additional adjustments for birth weight and maternal body mass index

From: Mild gestational diabetes in pregnancy and the adipoinsular axis in babies born to mothers in the ACHOIS randomised controlled trial

 

GDM

Not GDM

 

Treatment Group

Routine Care Group

Control Group

 

BW*

BW+BMI*

BW*

BW+BMI*

BW*

BW+BMI*

Plasma Glucose (mmol/ml)

4.7

0.2

4.7

0.2

4.8

0.2+

4.9

0.2+

4.3

0.2

4.3

0.2

Serum Insulin (μU/ml)^

2.0

0.2

2.1

0.2

2.1

0.2

2.1

0.2

2.0

0.1

2.0

0.1

Insulin to Glucose Ratio^

0.6

0.2

0.6

0.2

0.6

0.2

0.5

0.2

0.6

0.1

0.5

0.1

Serum Adiponectin (ng/ml)

22.1

2.2+

21.4

2.2+

23.0

2.0+

23.6

2.1+

27.0

1.7

27.8

1.8

Serum Leptin (ng/ml)^

2.4

0.1

2.4

0.1

2.5

0.1

2.5

0.1

2.4

0.1

2.5

0.1

Adiponectin to Leptin Ratio^

0.7

0.2

0.6

0.2

0.6

0.2

0.6

0.2

0.8

0.1

0.8

0.1

  1. Figures are mean, standard error
  2. BW = Birth weight
  3. BW + BMI = Birth weight + Maternal BMI
  4. * Results also adjusted for parity, smoking, gestational age at birth and sex, with additional adjustment for BW and BMI
  5. ^ Statistical analysis was performed on log-transformed data
  6. # p ≤ 0.05 versus GDM (Routine Care Group)
  7. + p ≤ 0.05 versus Control Group