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Table 1 Demographic and biochemical data of epileptic children at baseline and post-AED treatmenta

From: Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children- a medical center experience

Baseline

Overall gender (N)

 

 Male/Female

40/33

 Total

73

Age (yrs)

9.8 ± 4.1

Type of AEDs (N)

 

 Valproate

23

 Oxcarbazepine

29

 Valproate + Oxcarbazepine

21

Growth evaluation

 

 Height (cm)

133.5 ± 21.5

 Height-SDS

-0.2 ± 1.3

 Weight (kg)

35.0 ± 17.0

 Weight-SDS

0.5 ± 1.8

 Body mass index-SDS

1.1 ± 2.6

Laboratory studies

 

 Aspartate aminotransferase (U/L)

27.6 ± 7.5

 Alanine aminotransferase(U/L)

17.1 ± 7.8

 Blood urea nitrogen (mg/dL)

13.0 ± 1.2

 Creatinine (mg/dL)

0.5 ± 0.2

 Alkaline phosphatase (U/L)

226.8 ± 85.0

 Total calcium (mg/dL)

9.5 ± 0.4

 Free calcium (mg/dL)

4.9 ± 0.3

 Phosphorous (mg/dL)

4.7 ± 0.3

 Hemoglobin (g/dL)

13.0 ± 1.2

Post-treatment

Laboratory studies

 

 Serum TRAcP5b (umol/L/min)

4.8 ± 1.7

 TRAcP5b-SDS

-1.6 ± 1.2

 Serum BAP (umol/L/min)

144.4 ± 73.2

 BAP-SDS

1.7 ± 3.7

 Total calcium (mg/dL)

9.2 ± 0.3

 Free calcium (mg/dL)

4.7 ± 0.3

  1. aData presented as mean ± SD