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Table 2 Demographic and clinical data at the time of TDM measurement

From: Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target?

 

Culture proven sepsis

All

Male/female (n)

26/20

44/32

GA (weeks) mean ± SD

27.4 ± 3.3

28.9 ± 4.2

BW (g) mean ± SD

1100.0 ± 604.7

1346.9 ± 810.7

CW (g) mean ± SD

1104.2 ± 580.8

1316.8 ± 843.1

Patients (n)/TDM samples (n)

46/142

76/187

PMA (weeks) mean ± SD at first TDM

29.3 ± 4.1

30.9 ± 4.8

PNA (days) mean ± SD at first TDM

11 ± 11

12 ± 11

Mean creatinine concentration (μmol/L)

53 ± 23

51 ± 22

CPAP (%)

23

25

Mechanical ventilation (% of patients)

60

58

Vasoactive treatment (% of patients)

44

46

Vancomycin treatment duration (days)

10 ± 4

11 ± 4

LOS (n of episodes)

57

83

Died (n)

1

3