From: Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target?
Culture proven sepsis | All | |
---|---|---|
Male/female (n) | 26/20 | 44/32 |
GA (weeks) mean ± SD | 27.4 ± 3.3 | 28.9 ± 4.2 |
BW (g) mean ± SD | 1100.0 ± 604.7 | 1346.9 ± 810.7 |
CW (g) mean ± SD | 1104.2 ± 580.8 | 1316.8 ± 843.1 |
Patients (n)/TDM samples (n) | 46/142 | 76/187 |
PMA (weeks) mean ± SD at first TDM | 29.3 ± 4.1 | 30.9 ± 4.8 |
PNA (days) mean ± SD at first TDM | 11 ± 11 | 12 ± 11 |
Mean creatinine concentration (μmol/L) | 53 ± 23 | 51 ± 22 |
CPAP (%) | 23 | 25 |
Mechanical ventilation (% of patients) | 60 | 58 |
Vasoactive treatment (% of patients) | 44 | 46 |
Vancomycin treatment duration (days) | 10 ± 4 | 11 ± 4 |
LOS (n of episodes) | 57 | 83 |
Died (n) | 1 | 3 |