Table 1 Thrombolytic therapy
Thrombolytic agent | Therapeutic dose | Monitoring |
|---|---|---|
r-TPA | Start: 0.1 mg/kg/h iv Continuous infusion for longer periods with increasing doses if no improvement Max. dose: 0.5 mg/kg/h iv | Check CBC, APTT, PT, fibrinogen, D-dimers daily Exclude ICH by US daily Transfuse with FFP daily Maintain fibrinogen > 1.0 g/L and platelets > 50 × 109/L Check thrombus resolution once to twice daily |