Table 1 Patient demographics for each time epoch
Epoch 1 n = 159 | Epoch 2 n = 133 | Epoch 3 n = 252 | P | |
|---|---|---|---|---|
Gestational age (SD) | 26.8 (1.9) | 27.3 (1.9) | 27.2 (1.9) | 0.036 |
23–24 weeks | 38 (24%) | 14 (11%) | 47 (19%) | |
25–26 weeks | 39 (25%) | 43 (32%) | 55 (22%) | |
27–29 weeks | 82 (52%) | 76 (57%) | 150 (60%) | |
Birth weight (SD) | 911 (304) | 1011 (306) | 983 (300) | 0.012 |
≤ 750 g | 56 (35%) | 25 (19%) | 63 (25%) | |
751-999 g | 42 (62%) | 47 (35%) | 71 (28%) | |
≥ 1000 g | 61 (38%) | 61 (46%) | 118 (47%) | |
Sex - Male (n,%) | 84 (53%) | 75 (56%) | 131 (52%) | 0.705 |
SGA | 16 (10%) | 18 (14%) | 33 (13%) | 0.585 |
Maternal factors | ||||
Race | 0.005 | |||
Caucasian | 105 (66%) | 85 (64%) | 161 (64%) | |
Black | 10 (6%) | 3 (2%) | 5 (2%) | |
Hispanic | 24 (15%) | 34 (26%) | 71 (28%) | |
Other | 20 (13%) | 11 (8%) | 15 (6%) | |
Antenatal steroids - any | 154 (97%) | 130 (98%) | 244 (97%) | 0.865 |
Chorioamnionitis - clinical | 48 (30%) | 27 (20%) | 34 (13%) | < 0.001 |
Antibiotics – peripartum | 115 (72%) | 96 (72%) | 125 (50%) | < 0.001 |
Intrapartum Mg sulfate | 108 (68%) | 100 (75%) | 228 (90%) | < 0.001 |
C-section delivery | 110 (69%) | 87 (65%) | 189 (75%) | 0.121 |
Apgar Median (25–75%) | ||||
1 min | 5 (2–7) | 4 (2–7) | 4 (2–7) | 0.780 |
5 min | 7 (6–8) | 7 (6–8) | 7 (6–8) | 0.955 |
PDA treatment (n,%) | 57 (36%) | 40 (30%) | 65 (26%) | 0.094 |
Medical Only | 36 (63%) | 23 (58%) | 51 (78%) | 0.526 |
Surgical Ligation Only | 11 (19%) | 6 (15%) | 1 (2%) | 0.001 |
Medical & Surgical ligation | 10 (18%) | 11 (28%) | 13 (20%) | 0.487 |