Bacteriological profile and antibiotic susceptibility of neonatal sepsis in neonatal intensive care unit of a tertiary hospital in Nepal

Table 1 General characteristics of the enrolled neonates

Variables	EOS group	LOS group	Total	Percent	Fisher’s exact test p-value
Neonatal variables
Gender
Male	31	6	37	53.6	0.2571
Female	23	9	32	46.4	0.2571
Gestational age at birth
Preterm (< 37 weeks)	42	5	47	68.1	0.0033
Term (> 37 weeks)	12	10	22	31.9	0.0033
Birthweight
< 2500 g	34	10	44	63.8	1.0000
≥ 2500 g	20	5	25	36.2	1.0000
Mode of delivery
Vaginal	35	8	43	62.3	0.5484
Caesarean section	19	7	26	37.7	0.5484
APGAR score < 6 at 5 min	5	0	5	7.3	0.6250
Maternal variables
Maternal fever (within 7 days before delivery)	9	0	9	13.0	0.0039
PROM of > 18 h	29	2	31	44.9	< 0.0001
Foul smelling liquor	2	0	2	2.9	0.5000
Maternal antibiotics (within 7 days before delivery)	19	2	21	30.4	0.0002
Maternal GBS colonization	12	0	12	17.4	0.0004
Neonatal care related variables
Need for inotropes	39	2	41	59.4	< 0.0001
Need for positive pressure ventilation	54	10	64	92.8	< 0.0001
Central line	47	3	50	72.5	< 0.0001
Mortality	11	0	11	15.9	0.0009

EOS Early onset sepsis, GBS Group B Streptococcus, LOS Late onset sepsis, PROM Prolonged rupture of membrane

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