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Table 1 Signs and symptoms of serious illness as defined by NICE CG160 – “Fever in under 5s: assessment and initial” [1]

From: Point-of-care testing for procalcitonin in identifying bacterial infections in young infants: a diagnostic accuracy study

High Risk Features

Intermediate Risk Features

Pale/mottled/ashen/blue skin, lips or tongue

Pallor of skin, lips or tongue reported by parent or carer

No response to social cues

Not responding normally to social cues

Appearing ill to a healthcare professional

No smile

Does not wake or if roused does not stay awake

Wakes only with prolonged stimulation

Weak, high-pitched or continuous cry

Decreased activity

Grunting

Nasal flaring

Respiratory rate greater than 60 breaths per minute

Dry mucous membranes

Moderate or severe chest indrawing

Poor feeding in infants

Reduced skin turgor

Reduced urine output

Bulging fontanelle.

Rigors