Table 1 Baseline demographic and clinical characteristics in patients showing improvement in oxygenation without needing extracorporeal membrane oxygenation
Variable | iNO group n = 66 | Placebo group n = 38 | P value |
|---|---|---|---|
Birth weight, kg | |||
Mean (SD) | 3.3 (0.55) | 3.3 (0.65) | 0.902 |
Age at enrollment, hours | |||
Mean (SD) | 32.1 (20.63) | 30.8 (18.25) | 0.748 |
Male, n (%) | 28 (42.4) | 24 (63.2) | 0.042 |
Race or ethnic group, n (%) | 0.955 | ||
Black | 28 (42.4) | 14 (36.8) | |
Hispanic | 6 (9.1) | 4 (10.5) | |
White | 29 (43.9) | 18 (47.4) | |
Other | 3 (4.6) | 2 (5.3) | |
Primary pulmonary disease diagnosis, n (%) | |||
Meconium aspiration syndrome | 23 (34.8) | 14 (36.8) | |
Idiopathic pulmonary hypertension | 21 (31.8) | 15 (39.5) | |
Pneumonia | 15 (22.7) | 7 (18.4) | 0.794 |
Respiratory distress syndrome | 5 (7.6) | 1 (2.6) | |
Lung hypoplasia syndromes | 2 (3.0) | 1 (2.6) | |
PaO2, mmHg | |||
Mean (SD) | 87.8 (73.63) | 66.2 (41.35) | 0.058 |
Oxygenation index | |||
Mean (SD) | 28.5a (15.86) | 33.2 (15.5) | 0.154 |