From: Myocardial oedema in an 8-year-old Chinese boy with Idiopathic systemic capillary leak syndrome
Age (Years) | Sex | Clinical course | ECHO | Histopathology | ECMO support | Outcome | |
---|---|---|---|---|---|---|---|
Claessens et al 1998 [21] | 53 | M | Prodromal symptoms of chills, fever and cough, presented with shock, oedema | Global myocardial wall thickening Normal contractility Mild and non-compressive effusion | Not done | No | ECHO normalised within 3 days, alive |
Prodromal symptoms of cough, vomiting and shock | Myocardial wall enlargement Normal systolic function | Not done | No | ECHO normalised within 3 days, alive | |||
Juthier et al 2012 [20] | 41 | M | Known history of SCLS, presented with chest pain associated with ECG changes of ST segment elevation Developed sudden circulatory collapse | Left ventricular wall thickness was mildly increased Severely reduced right and left ventricle systolic function | Diffuse interstitial oedema. No inflammatory infiltrate and myocyte necrosis. | Yes | ECHO normalised in 17 days, alive |
Ertel et al 2015 [22] | 54 | M | Known ISCLS, presented with prodromal symptoms of upper respiratory tract infection, developed shock, multiple organ failure | Not available | (Post mortem) Diffuse oedema within the myocardial wall. Lace-like fibrosis of the interstitial space in the myocardium, consisted with sustained and/or recurrent, intermittent episodes of myocardial oedema No myocyte necrosis or lymphocytic infiltrates | No | Died |
Zancanaro et al 2015 [23] | 49 | M | Known ISCLS, presented after 2 days of sustained physical exertion with progressive oedema and hypotension, died after 15 hours with multiple organ failure and sudden cardiac arrest | Not available | (Post mortem) Myocardium with remarkable interstitial oedema with evidence of acute myocardial ischemia | No | Died |
Our case | 6 | M | Prodromal symptoms of gastroenteritis and presented with shock | Ventricular wall thickening suggestive of myocardial oedema | Not done | No | ECHO normalised within 1 month, alive |
8 | Prodromal symptoms of gastroenteritis and refractory shock | Ventricular wall thickening suggestive of myocardial oedema Poor systolic and diastolic function | Not done | Yes | ECHO normalised within 1 month, alive |