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Table 1 Cases of idiopathic systemic capillary leak syndrome with features suggestive of myocardial oedema

From: Myocardial oedema in an 8-year-old Chinese boy with Idiopathic systemic capillary leak syndrome

 

Age (Years)

Sex

Clinical course

ECHO

Histopathology

ECMO support

Outcome

Claessens et al 1998 [21]

53

M

Prodromal symptoms of chills, fever and cough, presented with shock, oedema

Global myocardial wall thickening

Normal contractility

Mild and non-compressive effusion

Not done

No

ECHO normalised within 3 days, alive

Prodromal symptoms of cough, vomiting and shock

Myocardial wall enlargement Normal systolic function

Not done

No

ECHO normalised within 3 days, alive

Juthier et al 2012 [20]

41

M

Known history of SCLS, presented with chest pain associated with ECG changes of ST segment elevation

Developed sudden circulatory collapse

Left ventricular wall thickness was mildly increased

Severely reduced right and left ventricle systolic function

Diffuse interstitial oedema.

No inflammatory infiltrate and myocyte necrosis.

Yes

ECHO normalised in 17 days, alive

Ertel et al 2015 [22]

54

M

Known ISCLS, presented with prodromal symptoms of upper respiratory tract infection, developed shock, multiple organ failure

Not available

(Post mortem)

Diffuse oedema within the myocardial wall.

Lace-like fibrosis of the interstitial space in the myocardium, consisted with sustained and/or recurrent, intermittent episodes of myocardial oedema

No myocyte necrosis or lymphocytic infiltrates

No

Died

Zancanaro et al 2015 [23]

49

M

Known ISCLS, presented after 2 days of sustained physical exertion with progressive oedema and hypotension, died after 15 hours with multiple organ failure and sudden cardiac arrest

Not available

(Post mortem)

Myocardium with remarkable interstitial oedema with evidence of acute myocardial ischemia

No

Died

Our case

6

M

Prodromal symptoms of gastroenteritis and presented with shock

Ventricular wall thickening suggestive of myocardial oedema

Not done

No

ECHO normalised within 1 month, alive

8

Prodromal symptoms of gastroenteritis and refractory shock

Ventricular wall thickening suggestive of myocardial oedema Poor systolic and diastolic function

Not done

Yes

ECHO normalised within 1 month, alive