Skip to main content

Table 3 Follow-up data of HIV infected children in HIV clinics at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia from April 1 to May 15, 2018 (n = 318)

From: Predictors of treatment failure, time to switch and reasons for switching to second line antiretroviral therapy in HIV infected children receiving first line anti-retroviral therapy at a Tertiary Care Hospital in Ethiopia

Variables

 

N (%)

Status Category

 Alive on ART

318 (92.4)

 Dead

26 (7.6)

Duration of follow up(month)

  ≤ 36

13 (4.1)

 37–59

31 (9.7)

  ≥ 60

274 (86.2)

Substitution of first line

 Yes

162 (50.9)

  Treatment failure

72 (44.4)

  New drug available

50 (30.8)

  Toxicity

23 (14.1)

  Drug stock out

6 (3.7)

  Change to fixed dose

6 (3.7)

  New TB diagnosis

2 (1.23)

  Others

3 (1.85)

 No

156 (49.05)

Time taken to initiate second line medication

  < 4 weeks

26 (36.1)

  ≥ 5 weeks

46 (63.8)

Adherence status of past 6 month

 Good

269 (84.5)

 Fair

37 (11.6)

 Poor

12 (3.7)

WHO T stage

 T1

289 (90.8)

 T2

7 (2.2)

 T3

1 (0.31)

 T4

21 (6.6)

Current CD4 count

 Not-significant immunosuppression

241(75.8)

 Mild-immunosuppression

49 (15.4)

 Advanced-immunosuppression

17 (5.3)

 Severe-immunosuppression

11 (3.5)

Viral load test

 Undetectable

268 (84.2)

  ≥ 150

24 (7.5)

 Missing data

26 (8.1)

Developed treatment failure to first line

 Yes

72 (22.6)

 Clinical failure only

2 2.7

 Immunological failure only

37 (51.3)

 Virologic failure only

6 (8.3)

 Clinical and immunological

24 (33.3)

 Virologic and immunologic

3 (4.17)

 No

246 (77.4)