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Table 1 Patient characteristics including comparison between patients with a non-obese body mass index (BMI) (non-obese group) and a BMI greater than the 95th percentile (obese group)

From: Quick assessment with controlled attenuation parameter for hepatic steatosis in children based on MRI-PDFF as the gold standard

 

All patients (n = 86)

Group comparison

Non-obese group (n = 33)

Obese group (n = 53)

p-value

Age (y)

13.1 ± 2.7

12.4 ± 2.4

13.5 ± 2.8

0.067

Female (n, %)

24 (31.3)

12 (36.4)

12 (22.6)

0.168*

BMI (kg/m2)

26.3 ± 4.9

21.6 ± 2.6

29.2 ± 3.5

< 0.001

AWT (cm)

2.5 ± 0.7

2.1 ± 0.5

2.8 ± 0.6

< 0.001

AST (U/L)

61.4 ± 49.7

46.2 ± 39.8

70.9 ± 53.2

0.015 †

ALT (U/L)

100.7 ± 85.2

71.2 ± 66.9

119.0 ± 90.7

0.004 †

Total bilirubin (mg/dL)

0.6 ± 0.3

0.5 ± 0.2

0.6 ± 0.3

0.861

Albumin (g/dL)

4.6 ± 0.3

4.6 ± 0.3

4.6 ± 0.2

0.702

ALP (IU/L)

206.5 ± 100.5

222.6 ± 99.0

196.5 ± 101.0

0.728

Cholesterol (mg/dL)

190.7 ± 35.9

185.8 ± 38.0

193.8 ± 34.5

0.229

TG (mg/dL)

159.5 ± 90.4

151.0 ± 86.0

163.3 ± 93.2

0.888†

HDL (mg/dL)

44.3 ± 10.0

45.8 ± 12.2

43.5 ± 8.7

0.501

LDL (mg/dL)

117.1 ± 34.4

113.9 ± 38.8

118.6 ± 32.3

0.356

PDFF (%)

22.6 ± 12.8

20.2 ± 14.5

24.1 ± 11.6

0.139

CAP (dB/m)

310.5 ± 46.5

293.6 ± 51.5

321.1 ± 40.2

0.053

  1. * Chi-square test was performed to compare the two groups
  2. †Logarithmic transformation before group comparison was performed in order to satisfy normality assumption. All the p-values of boldface are less than 0.05
  3. Notes: AWT abdominal wall thickness, AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase, TG triglycerides, HDL high-density lipoprotein, LDL low-density lipoprotein, PDFF proton density fat fraction, CAP controlled attenuation parameter