Neutrophil CD64 index in cerebrospinal fluid as a marker of bacterial ventriculitis in children with external ventricular drainage

Table 2 Median values with interquartile range of cerebrospinal fluid markers (CD64in, leukocyte count, percentage of neutrophils, glucose, proteins), and blood markers (leukocyte count, percentage of neutrophils and band neutrophils, CRP, and PCT) in ventriculitis and no-ventriculitis group

Laboratory markers	Ventriculitis group Median (IQR)	No-ventriculitis group Median (IQR)	p
CSF markers
CD64in	2.48 (1.64–4.6)	0.95 (0.75–1.39)	< 0.01*
Leukocyte count (× 10⁶/L)	225 (0–2491)	113 (1–1024)	0.03*
Percentage of neutrophils (%)	66 (0–96)	50 (0–99)	0.27
Glucose (mmol/L)	1.6 (0.1–4.1)	2.3 (0.8–6.7)	0.12
Proteins (g/L)	1.51 (0.46–4.2)	0.79 (0.19–4.85)	0.14
Blood markers
Leukocyte count (× 10⁹/L)	10.8 (5.1–26.8)	11.1 (2.7–18.3)	0.97
Percentage of neutrophils (%)	57 (22–86)	45 (15–81)	0.08
Percentage of band neutrophils (%)	2 (0–8)	0 (0–2)	0.05*
CRP (mg/L)	12 (0–330)	1.5 (0–162)	< 0.01*
PCT (μg/L)	0.25 (0.13–13.4)	0.17 (0.04–0.57)	0.14

*statistically significant differences, p < 0.05; IQR – interquartile range, CSF – cerebrospinal fluid, CD64in – neutrophil CD64 index, CRP – C-reactive protein, PCT – procalcitonin

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