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Table 5 Comparison of complications between infants with NEC stage I and those with ≥II after matching

From: Probiotics may not prevent the deterioration of necrotizing enterocolitis from stage I to II/III

Variables

Stage I (n = 123)

≥ Stage II (n = 39)

P

Neonatal respiratory syndrome, %(n)

8.1 (10)

2.6 (1)

0.402

Apnea, %(n)

4.1 (5)

7.7 (3)

0.626

Respiratory failure, %(n)

15.4 (19)

12.8 (5)

0.687

Pulmonary hemorrhage, %(n)

7.3 (9)

2.6 (1)

0.488

Sepsis, %(n)

30.9 (38)

51.3 (20)

0.021

Septic shock, %(n)

4.1 (5)

2.6 (1)

1.000

Bacterial meningitis, %(n)

5.7 (7)

5.1 (2)

1.000

Congenital heart disease, %(n)

46.3 (57)

48.7 (19)

0.796

Anemia, %(n)

69.9 (86)

64.1 (25)

0.496

Coagulation disorder, %(n)

59.3 (73)

56.4 (22)

0.745

Thrombocytopenia, %(n)

25.2 (31)

17.9 (7)

0.352

Cold injury syndrome, %(n)

3.3 (4)

5.1 (2)

0.957

Hypoproteinemia, %(n)

52.0 (64)

46.2 (18)

0.522

  1. We performed 1:1 matching according to close gestational age (difference was ≤3 days) and birth weight (difference was ≤400 g)