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Table 4 Diagnoses and hospitalization outcomes of newborns treated for risk of congenital syphilis

From: Better care for babies: the added value of a modified reverse syphilis testing algorithm for the treatment of congenital syphilis in a maternity Hospital in Central African Republic

 

RPRa Reactiveb

RPRa Non-reactivec

p-value

N=89

(%)

N=111

(%)

Discharge Diagnosesd

 None

65

(73)

82

(74)

NS

 Sepsis

8

(7)

2

(2)

0.02*

 Perinatal asphyxia

4

(4)

7

(8)

NS*

 Premature/low birth weight

3

(3)

3

(3)

NS*

 Antibiotic prophylaxis (well baby)e

9

(8)

15

(17)

NS

 HIV Exposure

4

(4)

9

(10)

NS

Number of diagnoses

 None

65

(73)

82

(74)

NS

 One diagnosis

20

(22)

22

(20)

NS

 Two diagnoses

4

(5)

7

(6)

NS*

Disposition

 Discharged

79

(89)

107

(96)

0.05

 Transferred

2

(2)

0

(0)

NS*

 Dead

2

(2)

1

(1)

NS*

 Left against medical advice

6

(7)

3

(3)

NS*

  1. X2 test used for all comparisons except where indicated as (*) Fisher’s exact test
  2. Neonatal treatment was based on Maternal RPR Results at MSF Castors Maternity Hospital from March 2017 to February 2018
  3. aRPR Rapid plasma reagin test b RPR reactive = titre > 1:4c RPR non-reactive = titre of 1:2
  4. dSum of n for discharge diagnoses is not equal to 100% as patients can present with more than one diagnosis
  5. NS = Not significant
  6. eAntibiotic prophylaxis = infants who are treated for a minimum of 48 h of antibiotics based on maternal and birth risk factors but who are otherwise well
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BMC Pediatrics

ISSN: 1471-2431

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