Table 1 Baseline characteristics of the levothyroxine nontreatment and treatment groups
From: Thyroid dysfunction in preterm infants born before 32 gestational weeks
Nontreatment N = 145 | Treatment N = 35 | p | Adjusted p* | |
|---|---|---|---|---|
Maternal age (years) | 32.6 ± 3.3 | 32.1 ± 3.6 | 0.408 | – |
Gestational age (weeks+days) | 27+ 5 ± 2+ 0 | 27+ 6 ± 2+ 0 | 0.931 | – |
Birth weight (g) | 1026 ± 329 | 935 ± 266 | 0.133 | – |
Male (%) | 79 (54.5) | 17 (48.6) | 0.529 | – |
Caesarean section (%) | 95 (65.5) | 29 (82.9) | 0.047 | – |
Multiple gestation (%) | 46 (31.7) | 6 (17.1) | 0.088 | – |
Antenatal corticosteroids (%) | 128 (88.3) | 32 (91.4) | 0.594 | – |
Premature rupture of membrane (%) | 70 (48.3) | 11 (31.4) | 0.072 | – |
Pregnancy-induced hypertension (%) | 24 (16.6) | 14 (40.0) | 0.002 | 0.045 |
Gestational diabetes (%) | 9 (6.2) | 0 (0.0) | 0.130 | – |
Maternal thyroid disease (%) | 1 (0.7) | 0 (0.0) | 1.000 | – |
1 min Apgar score | 4.0 ± 1.9 | 3.8 ± 1.9 | 0.586 | – |
5 min Apgar score | 6.1 ± 1.7 | 5.7 ± 1.7 | 0.274 | – |
Respiratory distress syndrome (%) | 112 (77.2) | 26 (74.3) | 0.711 | – |
Early-onset sepsis (%) | 1 (0.7) | 2 (5.7) | 0.097 | – |