Table 2 clinical features of six children with FS
From: Phenotypic variability in a child with Felty’s syndrome: a case report
Clinical features | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 |
|---|---|---|---|---|---|---|
Age at onset of JIA(Y) | 10.0 | 4.0 | 4.0 | 14.0 | 15.0 | 8.0 |
Gender | F | F | F | F | F | F |
JIA subtype | Polyarticular | Polyarticular | Polyarticular | Systemic | Polyarticular | Polyarticular |
Duration of JIA until FS(Y) | 5.8 | 11.0 | 4.5 | 10.0 | 2.0 | 4.0 |
Splenomegaly | Yes | Yes | Yes | Yes | Yes | Yes |
Hepatomegaly | No | No | No | Yes | Yes | Yes |
Hemoglobin(g/l) | Normal | 135.0 | 122.0 | 128.0 | 80.0 | 118.0 |
Platelet count (×109/l) | Not reported | 313.0 | 72.0 | 105.0 | 159.0 | 95.0 |
Leucocyte count (×109/l) | 1.8 | 4.1 | 2.8 | 2.7 | 4.1 | 6.2 |
Granulocyte count (× 109/l) | 0.5 | 1.7 | 1.3 | 1.5 | 3.1 | 3.92 |
RF (IU/l) | 1:480 Positive | Negative | Negative | Negative | Negative | 10,200.0 Positive |
Anti-CCP(U/l) | Not reported | Not reported | Not reported | Not reported | Negative | 384.0 |
Levels of complement | Normal | NA | Normal | NA | Normal | Normal |
ANA | 1:120 Positive | 1:320 Positive | Negative | Negative | Negative | 1:320 Positive |
Bone marrow findings | Normal | Normal | Normal | Normal | Normal | Normal |
Medications | MTX, Ibuprofen | Gold, HCQ, ASA | Tolmetin, ASA | Prednisolone, HCQ, Ibuprofen, MTX | MTX, HCQ, MP | Prednisolone, Diclofenac, HCQ, Sulfasalazine, MTX, Etanercept, Rituximab |
Reference | [4] | [5] | [6] | [7] | [8] | * |