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Table 3 Mechanical Ventilation and Respiratory Outcomes

From: Feasibility of combining two individualized lung recruitment maneuvers at birth for very low gestational age infants: a retrospective cohort study

 

VLGAI

29- to 31-wk stratum

ELGAI

Period 1

N = 91

Period 2

N = 72

Period 1

N = 43

Period 2

N = 30

Period 1

N = 48

Period 2

N = 42

MV in the first 72 h, n (%)

72 (79)

41 (57)*##

28 (65)

11 (37)*#

44 (92)

30 (71)*

Duration of MV within the first 72 h, h (median)

[1st Qu; 3rd Qu]

13

[3–48]

7*#

[0–30]

8

[0–17]

0

[0–13]

45

[9–72]

13**

[0–43]

Duration of MV, d (median)

[1st Qu; 3rd Qu]

1

[0–6]

1

[0–6]

0

[0–1]

0

[0–1]

5

[1–24]

4

[0–10]

Duration of NIV, d (median)

[1st Qu; 3rd Qu]

27

[6–40]

27

[8–35]

13

[3–28]

13

[7–25]

37

[26–45]

32

[23–39]

HFO, n (%)

26 (29)

34 (48)*##

2 (5)

6 (21)#

24 (50)

28 (67)#

2nd dose of Surfactant, n (%)

19 (21)

6 (8)*##

2 (5)

1 (3)

17 (35)

5 (12)*##

INSURE Procedure, n (%)

2 (2)

11 (15)*##

0 (0)

5 (17)*

2 (4)

6 (14)

Postnatal Corticosteroids, n (%)

28 (31)

9 (13)*##

3 (7)

1 (3)

25 (52)

8 (19)*##

  1. VLGAI Very low gestational age infants < 32 weeks, ELGAI Extremely low gestational age infants < 29 weeks, MV Mechanical ventilation, NIV Noninvasive ventilation, HFO High frequency oscillation, INSURE Intubation-surfactant-extubation; *: p < 0.05; **: p < 0.01; #: adjusted p < 0.05; ##: adjusted p < 0.01; *#: p and adjusted p < 0.05; *##: p and adjusted p < 0.01