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Table 3 Clinical Outcomes. NEC – Necrotising Enterocolitis; TANEC – Transfusion-Associated NEC (NEC within 48 h of transfusion)

From: FEEding DURing red cell transfusion (FEEDUR RCT): a multi-arm randomised controlled trial

 

Group 1

No feeds

Group 2

Full feeds

Group 3

Restricted feeds

p-value

Time to return to full feeds, hours ± SD

8 ± 35

13 ± 46

8 ± 32

0.88

Feed intolerance, n (%)

0

5 (25%)

1 (5%)

0.02*

Abdo distension, n (%)

1 (5%)

3 (15%)

2 (10%)

0.57

Adverse Events, n (%)

0

0

1 (5%)**

0.36

TANEC, n

0

0

0

n/a

NEC, n

0

0

0

n/a***

Late onset sepsis, n

11/19

10/18

7/17

n/a***

Mortality, n

0

0

0

n/a***

  1. *p < 0.05
  2. **1 infant treated for suspected NEC (managed conservatively; not proven)
  3. ***not appropriate to compare rates of long term outcomes as feeding allocation was for one transfusion only