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Table 2 Clinical manifestations and laboratory results of Henoch–Schönlein purpura patients with and without gastrointestinal involvement

From: Fecal calprotectin as a marker of gastrointestinal involvement in pediatric Henoch–Schönlein purpura patients: a retrospective analysis

Variable

Total HSP patients (n = 69)

Gastrointestinal involvement (n = 40)

Non-gastrointestinal involvement (n = 29)

P value

Age (years)

6.85 ± 2.93

7.11 ± 2.67

6.48 ± 3.27

0.380

Male sex

37 (53.6%)

21 (52.5%)

16 (55.2%)

0.826

Duration of admission (days)

5.41 ± 5.27

7.25 ± 6.05

2.79 ± 1.97

0.000*

Joint symptoms

35 (50.7%)

16 (40.0%)

19 (65.5%)

0.036*

Kidney involvement

16 (23.2%)

10 (25.0%)

6 (20.7%)

0.675

HSP clinical score

1.99 ± 1.53

2.65 ± 1.59

1.07 ± 0.80

0.000*

HSP recurrence

23 (33.3%)

15 (37.5%)

8 (27.6%)

0.389

Gastrointestinal symptom recurrence

19 (27.5%)

12 (30.0%)

7 (24.1%)

0.591

Positive stool occult blood result

17 (24.6%)

17 (42.5%)

0 (0%)

0.000*

Fecal calprotectin (mg/kg)

252.7 ± 343.8

379.9 ± 399.8

77.4 ± 97.6

0.000*

WBC count (106/L)

11,757 ± 5133

12,365 ± 6015

10,889 ± 3434

0.246

ANC (μL)

7673 ± 4388

8476 ± 4716

6526 ± 3652

0.071

ESR (mm/h)

23.74 ± 12.46

25.50 ± 12.62

21.04 ± 11.95

0.157

C-reactive protein (mg/L)

5.87 ± 6.39

5.18 ± 5.65

6.87 ± 7.31

0.285

FDP (μg/mL) (n = 57)

9.14 ± 9.16

11.08 ± 11.14

6.73 ± 5.07

0.064

D-dimer (μg/mL) (n = 57)

2.34 ± 2.45

2.93 ± 2.89

1.61 ± 1.50

0.036*

  1. HSP Henoch–Schönlein purpura, WBC White blood cell, ANC Absolute neutrophil count, ESR Erythrocyte sedimentation rate, FDP Fibrin degradation product
  2. *Significant findings at P < 0.05