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Table 2 Growth outcomes

From: The efficacy and safety of peripheral intravenous parenteral nutrition vs 10% glucose in preterm infants born 30 to 33 weeks’ gestation: a randomised controlled trial

Outcome P-PN (n = 42) Control (n = 50) Adjusted mean difference (95% CI) Adjusted P valuea
Weight gain from birth to day 21, g/d 18.7 (6.6) 14.8 (6.0) 3.9 (1.3 to 6.6) 0.004
Per protocol weight gain from birth to day 21, g/db 19.3 (6.3) 14.8 (6.1) 4.4 (1.9 to 7.0) 0.0008
Birthweight regained, d, (n = 41/49) 9.8 (2.9) 12.3 (2.8) 0.8 (0.7 to 0.9)c < 0.0001
Weight gain from birth to discharge home, g/d, (n = 42/49) 24.1 (5.3) 19.4 (8.4) 4.9 (2.0 to 7.8) 0.001
Length gain from birth to discharge home, mm/d, (n = 39/48) 1.2 (0.5) 1.0 (0.7) 0.3 (0.0 to 0.5) 0.02
Head circumference gain from birth to discharge home, mm/d, (n = 39/47) 0.9 (0.4) 0.9 (0.4) 0.1 (−0.1 to 0.2) 0.4
Weight at day 21, gd 2087 (332) 2042 (340) 76 (24 to 129) 0.004
Length at day 21 ± 2 days, cm, (n = 28/34)d 44.5 (2.8) 43.4 (2.1) 1.3 (0.5 to 2.1) 0.001
Head circumference at day 21 ± 2 days, cm, (n = 28/34)d 31.0 (2.0) 31.0 (1.4) 0.2 (−0.3 to 0.6) 0.5
Weight on discharge home, g, (n = 42/49)d 2561 (328) 2463 (359) 129 (4 to 254) 0.05
Length on discharge home, cm, (n = 39/48)d 45.8 (2.3) 45.3 (2.2) 0.7 (0.2 to 1.5) 0.1
Head circumference on discharge home, cm, (n = 39/47)d 32.8 (1.2) 32.8 (1.7) 0.1 (0.5 to 0.7) 0.7
  1. Data are presented as mean (SD)
  2. a Adjusted for sex and gestational age 30+ 0 to 31+ 6 and 32+ 0 to 33+ 6 weeks
  3. b Per protocol analysis included infants whose clinical care adhered to the study protocol, i.e. received P-PN and Control via peripheral line: P-PN n = 39, Control n = 49
  4. c Adjusted ratio of means
  5. d Additionally adjusted for corresponding anthropometric measure at birth