From: Incidence of neural tube defects and their risk factors within a cohort of Moroccan newborn infants
44 cases of NTDs | Anencephaly 22 (50%) | Spina Bifida 17 (38.6%) | Encephalocele 5 (11.4%) | |
---|---|---|---|---|
Maternel age | ||||
< 35 years | 33 (75) | 16 (72.7) | 14 (82.4) | 3 (60) |
≥ 35 years | 11 (25) | 6 (27.3) | 3 (17.6) | 2 (40) |
Socio-economic level | ||||
Low | 26 (59) | 12 (54.5) | 11 (64.7) | 3 (60) |
Middle | 15 (34) | 8 (36.4) | 5 (29.4) | 2 (40) |
High | 3 (6.8) | 2 (9.1) | 1 (5.9) | 0 |
Consanguinity | 15 (34) | 7 (31.8) | 5 (29.4) | 3 (60) |
First degree | 12 (27) | 5 (22.7) | 5 (29.4) | 2 (40) |
Second degree | 3 (6.8) | 2 (9) | 0 | 1 (20) |
Third degree | 0 | 0 | 0 | 0 |
Medical history | ||||
Diabetes | 1 (2.27) | 1 (4.5) | 0 | 0 |
Gestational Diabetes | 1 (2.27) | 0 | 1 (5.9) | 0 |
Malformation history in siblings | 2 (4.5) | 1 (4.5) | 0 | 1 (20) |
Malformation history in family | 3 (6.8) | 2 (9.1) | 0 | 1 (20) |
Fenugreek consumption | 10 (22.7) | 8 (36.4) | 2 (11.8) | 0 |
Other plants consumption | 6 (13.6) | 5 (22.7) | 1 (5.9) | 0 |
Medication | ||||
Paracetamol | 1 (2.27) | 0 | 1 (5.9) | 0 |
Folic acid supplementation | ||||
In preconception | 0 | 0 | 0 | 0 |
During the first trimester | 11 (25) | 5 (22.7) | 5 (29) | 1 (20) |
Pregnancy follow-up | 33 (75) | 15 (68.2) | 14 (82.4) | 4 (80) |
Gestational age | ||||
≤ 21WA | 3 (6.8) | 0 | 2 (11.8) | 1 (20) |
22-36WA | 9 (20.4) | 6 (27.3) | 2 (11.8) | 1 (20) |
≥ 37WA | 32 (72.7) | 16 (72.7) | 13 (76.4) | 3 (60) |
Prenatal diagnosis | 28 (63) | 17 (77.3) | 8 (47.1) | 3 (60) |
Mode of delivery | ||||
Normal | 36 (81.8) | 20 (90.9) | 11 (68.8) | 5 (100) |
Caesarean section | 7 (16) | 2 (9.1) | 5 (31.2) | 0 |
TIP | 4 (9.1) | 2 (9.1) | 1 (5.9) | 1 (20) |