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Table 1 Social, demographic and obstetrical characteristics of deformed newborns’ mothers and main risk factors at “Les Orangers” Maternity and Reproductive Health Hospital of Rabat, Morocco

From: Incidence of neural tube defects and their risk factors within a cohort of Moroccan newborn infants

 

44 cases of NTDs

Anencephaly

22 (50%)

Spina Bifida

17 (38.6%)

Encephalocele

5 (11.4%)

Maternel age

 < 35 years

33 (75)

16 (72.7)

14 (82.4)

3 (60)

 ≥ 35 years

11 (25)

6 (27.3)

3 (17.6)

2 (40)

Socio-economic level

 Low

26 (59)

12 (54.5)

11 (64.7)

3 (60)

 Middle

15 (34)

8 (36.4)

5 (29.4)

2 (40)

 High

3 (6.8)

2 (9.1)

1 (5.9)

0

Consanguinity

15 (34)

7 (31.8)

5 (29.4)

3 (60)

 First degree

12 (27)

5 (22.7)

5 (29.4)

2 (40)

 Second degree

3 (6.8)

2 (9)

0

1 (20)

 Third degree

0

0

0

0

Medical history

 Diabetes

1 (2.27)

1 (4.5)

0

0

 Gestational Diabetes

1 (2.27)

0

1 (5.9)

0

 Malformation history in siblings

2 (4.5)

1 (4.5)

0

1 (20)

 Malformation history in family

3 (6.8)

2 (9.1)

0

1 (20)

Fenugreek consumption

10 (22.7)

8 (36.4)

2 (11.8)

0

Other plants consumption

6 (13.6)

5 (22.7)

1 (5.9)

0

Medication

 Paracetamol

1 (2.27)

0

1 (5.9)

0

Folic acid supplementation

 In preconception

0

0

0

0

 During the first trimester

11 (25)

5 (22.7)

5 (29)

1 (20)

Pregnancy follow-up

33 (75)

15 (68.2)

14 (82.4)

4 (80)

Gestational age

 ≤ 21WA

3 (6.8)

0

2 (11.8)

1 (20)

 22-36WA

9 (20.4)

6 (27.3)

2 (11.8)

1 (20)

 ≥ 37WA

32 (72.7)

16 (72.7)

13 (76.4)

3 (60)

Prenatal diagnosis

28 (63)

17 (77.3)

8 (47.1)

3 (60)

Mode of delivery

 Normal

36 (81.8)

20 (90.9)

11 (68.8)

5 (100)

 Caesarean section

7 (16)

2 (9.1)

5 (31.2)

0

TIP

4 (9.1)

2 (9.1)

1 (5.9)

1 (20)

  1. NTDs neural tube defects, % percentage, WA week of amenorrhea, TIP therapeutic interruption of pregnancy