Table 3 Comparison of the outcomes at T2 assessment

TIMP score

113.54 ± 12.05^a

109.33 ± 11.01^a

101.18 ± 12.98^b

8.332

<0.001

DQ overall general score

90.56 ± 6.14

87.08 ± 10.34

85.06 ± 7.14

1.538

0.130

 Gross motor

94.50 ± 16.50

89.00 ± 17.71

84.94 ± 14.16

2.675

0.075

 Fine motor

90.36 ± 21.88

83.10 ± 21.54

81.55 ± 15.63

1.673

0.194

 Adaptive behavior

89.04 ± 19.13

90.55 ± 30.54

88.45 ± 21.00

0.062

0.940

 Personal-Social behavior

88.57 ± 22.56

88.31 ± 18.73

85.70 ± 25.86

0.153

0.858

 Language

90.57 ± 16.62

84.66 ± 13.74

84.67 ± 10.50

1.772

0.176

 Length (cm)

59.83 ± 2.77^a

58.61 ± 2.61^a

56.53 ± 2.45^b

12.614

<0.001

 Weight (kg)

5.56 ± 0.92^a

5.24 ± 0.95^a

4.74 ± 0.99^b

5.547

0.005

 Head circumference (cm)

38.91 ± 2.15^a

39.38 ± 1.93^a

38.20 ± 2.15^b

5.492

0.006