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Fig. 3 | BMC Pediatrics

Fig. 3

From: Neonatal systemic juvenile Xanthogranuloma with Hydrops diagnosed by Purpura skin biopsy: a case report and literature review

Fig. 3

Immunohistochemistry of the skin biopsy. It revealed the expression of CD68 and CD163 in the histiocytic population, whereas there was no expression of CD1a and Langerin. Hematoxylin and eosin staining showed an accumulation of histiocytes with several foamy cells (× 200 magnification) (a). The immunohistochemical staining pattern of histiocytes was follows: CD68 positive (brown staining, × 100 magnification) (b), CD163 positive (brown staining, × 100 magnification) (c), CD1a negative (no brown staining, × 100 magnification) (d), Langerin negative (no brown staining, × 100 magnification) (e)

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BMC Pediatrics

ISSN: 1471-2431

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