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Table 2 Comparison of standardized scores in each domain of guidelines and subgroups by AGREE II

From: Quality of pediatric clinical practice guidelines

Subject

Scope and purpose a

Stakeholder involvement a

Rigor of development a

Clarity of presentation a

Applicability a

Editorial independence a

Overall assessment a

Recommend b

Recommend with modification b

Not recommend b

Overall

55.16%

34.22%

28.62%

66.77%

21.26%

35.26%

4.26

6.48%

69.91%

23.61%

Country/ Region

 Developed

57.59%

35.79%

28.70%

68.32%

22.85%

38.37%

4.78

6.25%

77.08%

16.67%

 Developing

52.11%

32.26%

28.53%

65.53%

19.27%

31.38%

4.12

5.00%

64.17%

30.83%

p

0.001**

0.080

0.943

0.144

0.060

0.023*

0.052

0.055

Organization/ Group

 Yes

55.67%

34.32%

28.98%

68.35%

22.26%

34.93%

4.36

6.49%

72.43%

21.08%

 No

52.15%

33.60%

26.51%

57.35%

15.26%

37.23%

3.65

3.23%

54.84%

41.93%

p

0.083

0.801

0.470

< 0.001**

< 0.001**

0.595

< 0.001**

0.009

Evidence based

 Yes

56.41%

35.75%

31.88%

69.00%

22.70%

35.98%

4.48

7.41%

75.31%

17.28%

 No

51.39%

29.63%

18.85%

60.08%

16.94%

33.10%

3.59

1.85%

53.70%

44.45%

p

0.008**

< 0.001**

< 0.001**

< 0.001**

0.001**

0.358

< 0.001**

< 0.001

  1. AGREE II The Appraisal of Guidelines for Research and Evaluation II; a Continuous variable is presented as mean; b Categorical variable is reported as percentage; *p < 0.05 (two-sample t-test); **p < 0.01 (two-sample t-test); p < 0.01 (Person’s x2 test)