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Fig. 1 | BMC Pediatrics

Fig. 1

From: Neonatal intrahepatic cholestasis caused by citrin deficiency with no hepatic steatosis: a case report

Fig. 1

Pathological findings of liver tissue. a Hepatocyte swelling is notable. Bile plugs are also present. There is no fat deposition in the hepatocytes. b Cytokeratin 7 immunostaining shows a mild ductular reaction in the rim of the portal area and a clear interlobular bile duct. c Deposits of hemosiderin are found in the hepatocytes around the portal area. d Adipophilin immunostaining shows that the cytoplasm of the hepatocytes is positive, but perivacuolar staining is not highlighted (inset, positive control of fatty liver sample)

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