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Table 3 Morbidity prevalences and RRs stratified by BPD severity groups

From: Delineating morbidity patterns in preterm infants at near-term age using a data-driven approach

(a) AIRR

 

No BPD

Mild BPD

Moderate BPD

Severe BPD

 

n = 59

n = 58

n = 24

n = 30

PH

 Count

1 (1.69%)

4 (6.9%)

5 (20.83%)

5 (16.67%)

 RR

-

4.07 (0.47-35.32)

12.29 (1.51-99.77)

9.83 (1.20-80.43)

Mild cardiac defect

 Count

16 (27.12%)

17 (29.31%)

11 (45.83%)

14 (46.67%)

 RR

-

1.08 (0.61-1.93)

1.69 (0.92-3.09)

1.72 (0.98-3.03)

Perinatal brain pathology (mild)

 Count

10 (16.95%)

18 (31.03%)

7 (29.17%)

9 (30.0%)

 RR

-

1.83 (0.93-3.62)

1.72 (0.74-3.99)

1.77 (0.81-3.88)

Perinatal brain pathology (severe)

 Count

8 (13.56%)

8 (13.79%)

1 (4.17%)

3 (10.0%)

 RR

-

1.02 (0.41-2.53)

0.31 (0.04-2.33)

0.74 (0.21-2.58)

ROP (grades 1/2)

 Count

7 (11.86%)

10 (17.24%)

8 (33.33%)

13 (43.33%)

 RR

-

1.45 (0.59-3.56)

2.81 (1.15-6.89)

3.65 (1.63-8.18)

ROP (grades \(\ge\) 3)

 Count

1 (1.69%)

4 (6.9%)

1 (4.17%)

5 (16.67%)

 RR

-

4.07 (0.47-35.32)

2.46 (0.16-37.73)

9.83 (1.20-80.43)

(b) NEuroSIS

 

No BPD

Mild BPD

Moderate BPD

Severe BPD

 

n = 115

n = 94

n = 39

n = 111

PH

 Count

0 (0.0%)

1 (1.06%)

0 (0.0%)

3 (2.7%)

 RR

-

- (-)

- (-)

- (-)

Mild cardiac defect

 Count

46 (40.0%)

48 (51.06%)

25 (64.1%)

71 (63.96%)

 RR

-

1.28 (0.95-1.72)

1.6 (1.16-2.22)

1.6 (1.23-2.08)

Perinatal brain pathology (mild)

 Count

50 (43.48%)

42 (44.68%)

18 (46.15%)

60 (54.05%)

 RR

-

1.03 (0.76-1.40)

1.06 (0.71-1.58)

1.24 (0.95-1.63)

Perinatal brain pathology (severe)

 Count

10 (8.7%)

10 (10.64%)

6 (15.38%)

9 (8.11%)

 RR

-

1.22 (0.53-2.81)

1.77 (0.69-4.55)

0.93 (0.39-2.21)

ROP (grades 1/2)

 Count

38 (33.04%)

38 (40.43%)

16 (41.03%)

35 (31.53%)

 RR

-

1.22 (0.86-1.75)

1.24 (0.79-1.96)

0.95 (0.65-1.39)

ROP (grades \(\ge\) 3)

 Count

2 (1.74%)

11 (11.7%)

8 (20.51%)

25 (22.52%)

 RR

-

6.73 (1.53-29.61)

11.79 (2.62-53.20)

12.95 (3.14-53.39)

  1. Displayed for each BPD severity group are: morbidity count with the corresponding incidence relative to the size of the respective BPD severity group and the relative risk (RR) with the corresponding 95% confidence interval (CI). Statistically significant (i.e., CI does not include 1) RR values are indicated in bold