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Table 4 the comparison of mean (SD) secondary outcome between two groups in term of birth weight and gestational age subgroups

From: The impact of combined administration of surfactant and intratracheal budesonide compared to surfactant alone on bronchopulmonary dysplasia (BPD) and mortality rate in preterm infants with respiratory distress syndrome: a single-blind randomized clinical trial

Birth weight subgroup

Variables

Surfactant Group (n = 67)

Surfactant + Budesonide Group (n = 67)

P value*

Gestational age subgroup

Surfactant Group (n = 67)

Surfactant + Budesonide Group (n = 67)

P value*

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

< 1500 gr

N G1= 30 people

N G2=40 people

First -day- MAP (mmHg)

17.53 ± 1.30

16.57 ± 2.37

0.089

F = 4.66

< 30 weeks

N G1= 24 people

N G2=16 people

17.79 ± 0.93

16.88 ± 2.36

0.345 F = 2.95

Third -day – MAP (mmHg)

13.67 ± 2.84

9.21 ± 3.45

0.001

F = 34.14

14.65 ± 2.19

9.80 ± 3.61

0.001 F = 26.75

First -day- oxygen index (%)

18.60 ± 6.11

16.10 ± 0.8.39

0.090 F = 2.08

19.63 ± 5.32

18.06 ± 9.04

0.359 F = 0.47

Third -day- oxygen index (%)

6.71 ± 4.39

5.26 ± 4.48

0.045 F = 1.64

8.45 ± 4.11

5.47 ± 4.65

0.010 F = 4.23

First -day- Blood Sugar (mg/dL)

85.50 ± 22.24

78.53 ± 19.33

0.175 F = 1.87

87.54 ± 19.21

78.25 ± 18.51

0.137 F = 2.31

Third -day- Blood Sugar(mg/dL)

97.46 ± 24.14

93.80 ± 18.23

0.491 F = 0.47

97.17 ± 17.77

96.31 ± 18.01

0.883 F = 0.02

First -day- Mean Blood Pressure (mmHg)

33.45 ± 2.74

34.90 ± 4.54

0.058 F = 2.75

31.88 ± 1.60

33.13 ± 4.69

0.700 F = 1.46

Third -day- Mean Blood Pressure (mmHg)

35.72 ± 2.61

36.70 ± 2.81

0.046 F = 2.25

34.91 ± 2.13

35.69 ± 2.85

0.263 F = 0.94

1500–2000 gr

N G1= 22 people

N G2=13 people

First -day- MAP (mmHg)

16.16 ± 1.68

14.50 ± 2.26

0.062

F = 5.22

30–34 weeks

N G1= 39 people

N G2=32 people

16.47 ± 1.80

14.95 ± 2.38

0.003 F = 8.87

Third -day – MAP (mmHg)

8.38 ± 4.07

6.77 ± 1.95

0.853 F = 2.51

10.09 ± 4.05

7.18 ± 2.43

0.012 F = 14.06

First -day- oxygen index (%)

12.15 ± 6.44

10.41 ± 4.44

0.647 F = 0.90

14.16 ± 7.14

11.38 ± 5.43

0.175 F = 3.44

Third -day- oxygen index (%)

3 ± 3.10

2.90 ± 3.85

0.749 F = 0.01

3.44 ± 3.37

3.34 ± 4.16

0.691 F = 0.01

First -day- Blood Sugar (mg/dL)

93.38 ± 18.62

88.0 ± 20.41

0.442 F = 0.60

90.22 ± 22.08

86 ± 21.24

0.416 F = 0.66

Third -day- Blood Sugar (mg/dL)

99.0 ± 17.21

95.32 ± 17.75

0.553 F = 0.35

100.88 ± 24.86

94.10 ± 17.48

0.183 F = 1.80

First -day- Mean Blood Pressure (mmHg)

37.31 ± 4.92

38.73 ± 2.66

0.578 F = 1.23

37.38 ± 4.12

38.44 ± 3.21

0.207 F = 1.48

Third -day- Mean Blood Pressure (mmHg)

39.38 ± 3.97

40.18 ± 3

0.353 F = 0.45

38.75 ± 3.70

39.87 ± 3.92

0.122 F = 1.81

2000–2500 gr

N G1= 15 people

N G2=14 people

First -day- MAP (mmHg)

15.36 ± 1.28

14.73 ± 1.98

0.451

F = 0.99

34–37 weeks

N G1= 12 people

N G2=11 people

15.64 ± 1.21

15.33 ± 2.10

0.786 F = 0.17

Third -day – MAP (mmHg)

6.21 ± 0.58

6.27 ± 0.59

0.621 F = 0.05

6.27 ± 0.65

6.92 ± 1.98

0.397 F = 1.06

First -day- oxygen index (%)

7.79 ± 3.47

9.27 ± 3.24

0.186 F = 1.41

7.91 ± 3.70

9.83 ± 4.93

0.487 F = 1.10

Third -day- oxygen index (%)

1.61 ± 0.59

1.83 ± 0.62

0.505 F = 1.01

1.86 ± 0.50

2.64 ± 2.72

0.976 F = 0.87

First -day- Blood Sugar

85.0 ± 18.36

92.33 ± 23.84

0.364 F = 0.85

76 ± 17.97

89.25 ± 24.39

0.156 F = 2.16

Third -day- Blood Sugar (mg/dL)

99.43 ± 17.93

98.13 ± 14.08

0.830 F = 0.04

92.45 ± 17.93

97.67 ± 15.39

0.462 F = 0.56

First -day- Mean Blood Pressure (mmHg)

42.29 ± 2.61

43.47 ± 2.97

0.290 F = 1.28

41.27 ± 3.85

43.50 ± 3.66

0.235 F = 2.02

Third -day- Mean Blood Pressure (mmHg)

43.86 ± 2.21

44.20 ± 2.46

0.561 F = 0.15

43.27 ± 3.90

43.50 ± 3.15

0.928 F = 0.02

  1. * Analysis of variance (ANOVA)