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Table 1 Baseline perinatal and neonatal characteristics of infants with NRF according to birth weight

From: The current clinical landscape of neonatal respiratory failure in Jiangsu Province of China: patient demographics, NICU treatment interventions, and patient outcomes

 

Total

( n = 5584)

BW, g

< 1000

( n = 314)

1000 – 1499

( n = 1186)

1500 – 2499

( n = 2433)

2500 – 3999

( n = 1535)

≥ 4000

( n = 116)

P -value

Gestational age (week)

33.4 ± 3.6

27.8 ± 1.9*

30 ± 1.8*

32.9 ± 1.8*

37.5 ± 2.2

39.2 ± 1.6*

< 0.001

BW (g)

2105 ± 840

859 ± 100*

1274 ± 140*

1941 ± 285*

3088 ± 403

4365 ± 477*

< 0.001

Male, n (%)

3347(59.9)

175(56)*

650(54.8)*

1438(59.1)*

999(64.9)

85(73.3)

< 0.001

Cesarean delivery, n(%)

3664(65.60)

158(50.60)*

711(59.90)*

1688(69.30)

1081(66.20)

89(76.70)

< 0.001

Fetal distress, n(%)

564(11.2)

34(12.6)

112(11.0)*

206(9.2)*

193(13.8)

19(3.8)

< 0.001

Congenital anomalies, n(%)

103(1.8%)

11(3.5%)

18(1.5%)

39(1.6%)

32(2%)

3(2.5%)

0.127

Antenatal steroid usea, n(%)

1594(33.2)

126(46.8)*

519(51.0)*

830(39.5)*

117(8.9)

2(2.0)*

< 0.001

Gestational diabetes, n(%)

907(16.2)

39(12.5)

205(17.2)

381(15.6)

240(15.6)

42(36.2)*

< 0.001

Gestational hypertension, n(%)

770(13.7)

89(28.5)*

226(19)*

328(13.4)*

117(7.6)

10(8.6)

< 0.001

Premature rupture of membrane > 24 h, n(%)

550(9.8)

31(9.9)*

159(13.4)*

288(11.8)*

67(4.3)

5(4.3)

< 0.001

Apgar score at 1 min

8(7, 9)

6(4, 8)*

8(6, 8)*

8(7, 9)*

9(8, 9)

8(7, 9)*

< 0.001

Apgar score at 5 min

9(8, 10)

8(6, 9)*

8(8, 9)*

9(8, 10)*

9(8, 10)

9(8, 10)

< 0.001

PS in delivery room, n(%)

54(0.9)

4(1.2)

19(1.6)

18(0.7)

12(0.7)

1(0.8)

0.127

Positive pressure ventilation in the delivery room, n(%)

1096(19.6)

105(33.6)*

295(24.8)*

420(17.2)

252(16.3)

24(20.6)

< 0.001

Endotracheal intubation in delivery room, n(%)

475(8.5)

81(25.9)*

114(9.6)*

129(5.3)*

138(8.9)

13(11.2)

< 0.001

Chest compressions in the delivery room, n(%)

235(4.2)

29(9.2)*

62(5.2)

68(2.7)*

64(4.1)

12(10.3)*

< 0.001

  1. Abbreviations: NRF Neonatal respiratory failure, BW Birth weight, PS Pulmonary surfactant
  2. P-values derived from Kruskal-Wallis H or Chi-square test
  3. *Statistically significant difference (P < 0.05) compared to the normal BW group (2500 – 3999 g)
  4. a“Antenatal steroid use” refer to complete or partial antenatal steroid use